Retinoblastoma Binding Protein 4 (RBBP4) (C-Term) Peptid
Kurzübersicht für Retinoblastoma Binding Protein 4 (RBBP4) (C-Term) Peptid (ABIN8110378)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Verwendungszweck
- RBBP4 Peptide - C-terminal region
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Sequenz
- KISDFSWNPN EPWVICSVSE DNIMQVWQMA ENIYNDEDPE GSVDPEGQGS
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-RBBP4 Antibody (ARP74776_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Retinoblastoma Binding Protein 4 (RBBP4)
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Hintergrund
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Background Information: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: NURF55, RBAP48, lin-53
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Molekulargewicht
- 48 kDa
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Gen-ID
- 5928
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NCBI Accession
- NP_001128727
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UniProt
- Q09028
Target
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