Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) (N-Term) Peptid
Kurzübersicht für Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) (N-Term) Peptid (ABIN8104084)
Target
Quelle
Applikation
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Protein Region
- N-Term
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Verwendungszweck
- CSEN Peptide - N-terminal region
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-CSEN antibody ( ARP31932_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
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Hintergrund
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Background Information: CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Alternative Symbols: CSEN, DREAM, KCHIP3
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Molekulargewicht
- 29kDa
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Gen-ID
- 30818
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NCBI Accession
- NP_038462
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UniProt
- Q9Y2W7
Target
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