Kalirin, RhoGEF Kinase (KALRN) (Middle Region) Peptid
Kurzübersicht für Kalirin, RhoGEF Kinase (KALRN) (Middle Region) Peptid (ABIN8103609)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Verwendungszweck
- KALRN Peptide - middle region
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Sequenz
- GRKSFDLGSP KPGDETTPQG DSADEKSKKG WGEDEPDEES HTPLPPPMKI
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti- KALRN Antibody (ARP81502_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- KALRN (Kalirin, RhoGEF Kinase (KALRN))
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Hintergrund
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Background Information: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described.
Alternative Symbols: DUO, CHD5, DUET, TRAD, CHDS5, HAPIP, ARHGEF24
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Molekulargewicht
- 81 kDa
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Gen-ID
- 8997
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NCBI Accession
- NP_001019831
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UniProt
- O60229
Target
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