Interferon Regulatory Factor 8 (IRF8) (Middle Region) Peptid
Kurzübersicht für Interferon Regulatory Factor 8 (IRF8) (Middle Region) Peptid (ABIN8103269)
Target
Quelle
Applikation
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Protein Region
- Middle Region
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Verwendungszweck
- IRF8 Peptide - middle region
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-IRF8 antibody ( P100842_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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Hintergrund
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Background Information: Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.
Alternative Symbols: H-ICSBP, ICSBP, ICSBP1, IRF-8
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Molekulargewicht
- 48kDa
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Gen-ID
- 3394
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NCBI Accession
- NP_002154
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UniProt
- Q02556
Target
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