Iduronate 2-Sulfatase (IDS) (N-Term) Peptid
Kurzübersicht für Iduronate 2-Sulfatase (IDS) (N-Term) Peptid (ABIN8102928)
Target
Spezies
Quelle
Applikation
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Protein Region
- N-Term
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Verwendungszweck
- IDS Peptide - N-terminal region
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Sequenz
- SFPPYHPSSE KYENTKTCRG PDGELHANLL CPVDVLDVPE GTLPDKQSTE
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-IDS Antibody (ARP60956_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- IDS (Iduronate 2-Sulfatase (IDS))
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Hintergrund
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Background Information: Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
Alternative Symbols: MPS2, SIDS
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Molekulargewicht
- 59kDa
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Gen-ID
- 3423
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NCBI Accession
- NP_000193
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UniProt
- P22304
Target
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