Hemoglobin, gamma G (HBG2) (Middle Region) Peptid
Kurzübersicht für Hemoglobin, gamma G (HBG2) (Middle Region) Peptid (ABIN8102342)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Verwendungszweck
- HBG2 Peptide - middle region
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Sequenz
- MGNPKVKAHG KKVLTSLGDA IKHLDDLKGT FAQLSELHCD KLHVDPENFK
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-HBG2 Antibody (ARP64733_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HBG2 (Hemoglobin, gamma G (HBG2))
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Hintergrund
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Targeted Subunit: gamma-2
Background Information: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Alternative Symbols: FLJ76540
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Molekulargewicht
- 16kDa
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Gen-ID
- 3048
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NCBI Accession
- NP_000175
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UniProt
- P69892
Target
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