GLI Pathogenesis-Related 1 (GLIPR1) (Middle Region) Peptid
Kurzübersicht für GLI Pathogenesis-Related 1 (GLIPR1) (Middle Region) Peptid (ABIN8101495)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Verwendungszweck
- GLIPR1 Peptide - middle region
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Sequenz
- SLGENIWTGS VPIFSVSSAI TNWYDEIQDY DFKTRICKKV CGHYTQVVWA
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-GLIPR1 Antibody (ARP64655_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))
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Hintergrund
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Background Information: This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
Alternative Symbols: CRISP7, GLIPR, RTVP1
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Molekulargewicht
- 28kDa
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Gen-ID
- 11010
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NCBI Accession
- NP_006842
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UniProt
- P48060
Target
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