Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (Middle Region) Peptid
Kurzübersicht für Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (Middle Region) Peptid (ABIN8101344)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Verwendungszweck
- FGR Peptide - middle region
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Sequenz
- LLSPGNPQGA FLIRESETTK GAYSLSIRDW DQTRGDHVKH YKIRKLDMGG
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Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) peptide
FGR Reaktivität: Human, Maus, Ratte, Hund Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti- FGR Antibody (ARP83961_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
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Hintergrund
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Background Information: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alternative Symbols: SRC2, c-fgr, c-src2, p55-Fgr, p58-Fgr, p55c-fgr, p58c-fgr
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Molekulargewicht
- 58 kDa
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Gen-ID
- 2268
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NCBI Accession
- NP_001036194
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UniProt
- P09769
Target
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