FK506 Binding Protein 3, 25kDa (FKBP3) Peptid
Kurzübersicht für FK506 Binding Protein 3, 25kDa (FKBP3) Peptid (ABIN8100736)
Target
Quelle
Applikation
-
-
Verwendungszweck
- FKBP3 Peptide
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
This is a synthetic peptide designed for use in combination with anti-FKBP3 antibody ( ARP54612_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))
-
Hintergrund
-
Background Information: FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Alternative Symbols: FKBP-25, PPIase, FKBP-3, FKBP25
-
Molekulargewicht
- 25kDa
-
Gen-ID
- 2287
-
NCBI Accession
- NP_002004
-
UniProt
- Q00688
Target
-