DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (Middle Region) Peptid
Kurzübersicht für DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (Middle Region) Peptid (ABIN8098884)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Verwendungszweck
- DGCR8 Peptide - middle region
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Sequenz
- TEEKYGGDSD HPSDGETSVQ PMMTKIKTVL KSRGRPPTEP LPDGWIMTFH
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-DGCR8 Antibody (ARP74483_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
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Hintergrund
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Background Information: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
Alternative Symbols: DGCR8,C22orf12, DGCRK6,LP4941,
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Molekulargewicht
- 85kDa
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Gen-ID
- 54487
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NCBI Accession
- NP_073557
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UniProt
- Q8WYQ5
Target
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