Deleted in Azoospermia-Like (DAZL) (C-Term) Peptid
Kurzübersicht für Deleted in Azoospermia-Like (DAZL) (C-Term) Peptid (ABIN8098742)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Verwendungszweck
- DAZL Peptide - C-terminal region
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Sequenz
- PPSGNGPQKK SVDRSIQTVV SCLFNPENRL RNSVVTQDDY FKDKRVHHFR
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Deleted in Azoospermia-Like (DAZL) peptide
DAZL Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-DAZL Antibody (ARP40355_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- DAZL (Deleted in Azoospermia-Like (DAZL))
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Hintergrund
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Background Information: DAZ (Deleted in AZoospermia) is the potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. DAZL is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of the autosomal gene encoding DAZL during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in the Dazl gene have been linked to severe spermatogenic failure and infertility in males.
Alternative Symbols: DAZL
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Molekulargewicht
- 32kDa
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Gen-ID
- 1618
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NCBI Accession
- NP_001342
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UniProt
- Q92904
Target
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