Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (Middle Region) Peptid
Kurzübersicht für Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (Middle Region) Peptid (ABIN8096343)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Verwendungszweck
- CASP9 Peptide - middle region
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Sequenz
- QKDHGFEVAS TSPEDESPGS NPEPDATPFQ EGLRTFDQLD AISSLPTPSD
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-CASP9 Antibody (ARP72517_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Hintergrund
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Background Information: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1, this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Alternative Symbols: CASP9, MCH6,
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Molekulargewicht
- 29kDa
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Gen-ID
- 842
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UniProt
- P55211
Target
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