Cadherin 8 (CDH8) (C-Term) Peptid
Kurzübersicht für Cadherin 8 (CDH8) (C-Term) Peptid (ABIN8095896)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Verwendungszweck
- CDH8 Peptide - C-terminal region
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Sequenz
- QIYGYEGRGS VAGSLSSLES TTSDSDQNFD YLSDWGPRFK RLGELYSVGE
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti- CDH8 Antibody (ARP84819_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Cadherin 8 (CDH8)
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Hintergrund
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Background Information: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Alternative Symbols: Nbla04261
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Molekulargewicht
- 87 kDa
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Gen-ID
- 1006
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NCBI Accession
- NP_001787
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UniProt
- P55286
Target
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