Bruton Agammaglobulinemia tyrosine Kinase (BTK) (N-Term) Peptid
Kurzübersicht für Bruton Agammaglobulinemia tyrosine Kinase (BTK) (N-Term) Peptid (ABIN8095736)
Target
Spezies
Quelle
Applikation
-
-
Protein Region
- N-Term
-
Verwendungszweck
- BTK Peptide - N-terminal region
-
Sequenz
- LTVHKLSYYE YDFERGRRGS KKGSIDVEKI TCVETVVPEK NPPPERQIPR
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
This is a synthetic peptide designed for use in combination with anti-BTK Antibody (ARP79105_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
-
Hintergrund
-
Background Information: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Symbols: AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1
-
Molekulargewicht
- 53 kDa
-
Gen-ID
- 695
-
NCBI Accession
- NP_000052
-
UniProt
- Q5JY90
Target
-
