BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptid
Kurzübersicht für BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptid (ABIN8095547)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Verwendungszweck
- BID Peptide - C-terminal region
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Sequenz
- LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH
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BH3 Interacting Domain Death Agonist (BID) peptide
BID Reaktivität: Human Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-BID Antibody (ARP61037_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- BID (BH3 Interacting Domain Death Agonist (BID))
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Hintergrund
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Background Information: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Alternative Symbols: FP497, MGC15319, MGC42355
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Molekulargewicht
- 27kDa
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Gen-ID
- 637
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NCBI Accession
- NP_932070
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UniProt
- B3KT21
Target
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