beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Peptid
Kurzübersicht für beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Peptid (ABIN8095537)
Target
Spezies
Quelle
Applikation
-
-
Protein Region
- Middle Region
-
Verwendungszweck
- BACE2 Peptide - middle region
-
Sequenz
- SLNLDCREYN ADKAIVDSGT TLLRLPQKVF DAVVEAVARA SLIPEFSDGF
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
This is a synthetic peptide designed for use in combination with anti-BACE2 Antibody(ARP46852_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
-
Hintergrund
-
Background Information: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
Alternative Symbols: AEPLC, ALP56, ASP1, ASP21, BAE2, CDA13, CEAP1, DRAP
-
Molekulargewicht
- 37kDa
-
Gen-ID
- 25825
-
NCBI Accession
- NP_620477
-
UniProt
- Q9Y5Z0
Target
-
