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omega-agatoxin IVA Peptid

Reaktivität: Agelenopsis aperta Wirt: Synthetic
Produktnummer ABIN7887366
347,69 €
Zzgl. Versandkosten 20,00 € und MwSt
Lieferung nach: Deutschland
Lieferung in 8 bis 9 Werktagen

Kurzübersicht für omega-agatoxin IVA Peptid (ABIN7887366)

Target

omega-agatoxin IVA

Spezies

Agelenopsis aperta

Quelle

  • 2
Synthetic
  • Protein-Typ

    Synthetic

    Biologische Aktivität

    Active

    Verwendungszweck

    ω-Agatoxin IVA

    Sequenz

    KKKCIAKDYG RCKWGGTPCC RGRGCICSIM GTNCECKPRL IMEGLGLA-OH

    Spezifität

    Toxin target: P/Q-type calcium channels (CaV2.1)

    Reinheit

    ≥98 % (HPLC)

    Biological Activity Comment

    ω-Agatoxin IVA is an antagonist of voltage-sensitive P-type Ca2+ channels1. It blocks neuromuscular transmission presynaptically in a variety of synapses2,3.
  • Applikationshinweise

    Antigen Preadsorption Control: 20 nM - 1 μM

    Kommentare

    Electrophysiology

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial and dissolve by gently tapping, tilting, or rolling the vial. Avoid vigorous vortexing, a brief, light vortex of 1-2 seconds is acceptable if necessary. The product is readily soluble in high-quality pure water at micromolar to millimolar concentrations (typically 100 μM to 1  mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x the final working concentration. Divide the stock solution into small, single-use aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh working solutions just before use. Avoid multiple freeze-thaw cycles to maintain optimal biological activity.

    Buffer

    Lyophilized from double distilled water (ddH2O). May contain residual trifluoroacetate (TFA).

    Handhabung

    Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom,Avoid multiple freeze-thaw cycles to maintain optimal biological activity,Avoid vigorous vortexing. protect from moisture

    Lagerung

    -20 °C

    Informationen zur Lagerung

    The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.
  • Target

    omega-agatoxin IVA

    Hintergrund

    A potent and selective blocker of P/Q-type (CaV2.1) calcium channels

    Molekulargewicht

    5202 Da

    UniProt

    P30288

    CAS-Nummer

    145017-83-0
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