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Uracil-DNA Glycosylase (UNG) (N-Term) Peptid

UNG Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5673998

Kurzübersicht für Uracil-DNA Glycosylase (UNG) (N-Term) Peptid (ABIN5673998)

Target

UNG (Uracil-DNA Glycosylase (UNG))

Spezies

Human

Quelle

  • 2
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    LYSFFSPSPA RKRHAPSPEP AVQGTGVAGV PEESGDAAAI PAKKAPAGQE

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- UNG Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    UNG (Uracil-DNA Glycosylase (UNG))

    Substanzklasse

    Viral Protein

    Hintergrund

    This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.

    Alias Symbols: DGU, UDG, UNG1, UNG2, HIGM4, HIGM5, UNG15

    Protein Size: 313

    Gen-ID

    7374

    NCBI Accession

    NM_003362, NP_003353

    UniProt

    P13051
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