Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11) (C-Term) Peptid
DUSP11
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle DUSP11 Produkte
- DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- HTQTQSLQQS VRKFSENPHV YQRHHLPPPG PPGEDYSHRR YSWNVKPNAS
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- DUSP11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))
- Hintergrund
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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.
Alias Symbols: PIR1
Protein Size: 330 - Gen-ID
- 8446
- NCBI Accession
- NM_003584, NP_003575
- UniProt
- O75319
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