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tRNA-Histidine Guanylyltransferase 1-Like (THG1L) (Middle Region) Peptid

THG1L Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5673680

Kurzübersicht für tRNA-Histidine Guanylyltransferase 1-Like (THG1L) (Middle Region) Peptid (ABIN5673680)

Target

THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    DGRVVVYPSN QTLKDYLSWR QADCHINNLY NTVFWALIQQ SGLTPVQAQG

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- THG1L Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))

    Hintergrund

    The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: ICF45, IHG-1, hTHG1

    Protein Size: 298

    Gen-ID

    54974

    NCBI Accession

    NM_017872, NP_060342

    UniProt

    Q9NWX6
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