phosphodiesterase 11A (PDE11A) (Middle Region) Peptid
PDE11A
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5673488
Kurzübersicht für phosphodiesterase 11A (PDE11A) (Middle Region) Peptid (ABIN5673488)
Target
PDE11A
(phosphodiesterase 11A (PDE11A))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- GKGIIGYVGE HGETVNIPDA YQDRRFNDEI DKLTGYKTKS LLCMPIRSSD
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- PDE11A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PDE11A (phosphodiesterase 11A (PDE11A))
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Hintergrund
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The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PPNAD2
Protein Size: 933 -
Gen-ID
- 50940
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NCBI Accession
- NM_001077196, NP_001070664
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UniProt
- Q9HCR9
Target
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