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phosphodiesterase 11A (PDE11A) (Middle Region) Peptid

PDE11A Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5673488
  • Target Alle PDE11A Produkte
    PDE11A (phosphodiesterase 11A (PDE11A))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 11
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    GKGIIGYVGE HGETVNIPDA YQDRRFNDEI DKLTGYKTKS LLCMPIRSSD
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- PDE11A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PDE11A (phosphodiesterase 11A (PDE11A))
    Hintergrund
    The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: PPNAD2

    Protein Size: 933
    Gen-ID
    50940
    NCBI Accession
    NM_001077196, NP_001070664
    UniProt
    Q9HCR9
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