phospholipid Scramblase 3 (PLSCR3) (N-Term) Peptid
PLSCR3
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5673450
Kurzübersicht für phospholipid Scramblase 3 (PLSCR3) (N-Term) Peptid (ABIN5673450)
Target
PLSCR3
(phospholipid Scramblase 3 (PLSCR3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- PPKGYAPSPP PPYPVTPGYP EPALHPGPGQ APVPAQVPAP APGFALFPSP
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- PLSCR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
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Hintergrund
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May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Protein Size: 295 -
Gen-ID
- 57048
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NCBI Accession
- NM_001201576, NP_001188505
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UniProt
- Q9NRY6
Target
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