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Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (Middle Region) Peptid

UBE2V1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5673384

Kurzübersicht für Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (Middle Region) Peptid (ABIN5673384)

Target

UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    IYENRIYSLK IECGPKYPEA PPFVRFVTKI NMNGVNSSNG VVDPRAISVL

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- UBE2V1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

    Hintergrund

    Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

    Alias Symbols: CIR1, UEV1, CROC1, UBE2V, UEV-1, UEV1A, CROC-1

    Protein Size: 221

    Gen-ID

    7335

    NCBI Accession

    NM_001032288, NP_001027459
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