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Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (Middle Region) Peptid

PARK2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5673381
  • Target Alle Parkin (PARK2) Produkte
    Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 8
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    GKELRNDWTV QNCDLDQQSI VHIVQRPWRK GQEMNATGGD DPRNAAGGCE
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- PARK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
    Hintergrund
    The precise function of this gene is unknown, however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]

    Alias Symbols: PDJ, AR-JP, LPRS2, PARK2

    Protein Size: 465
    Gen-ID
    5071
    NCBI Accession
    NM_004562, NP_004553
    UniProt
    O60260
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