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Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) (N-Term) Peptid

EEF1E1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5673210

Kurzübersicht für Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) (N-Term) Peptid (ABIN5673210)

Target

EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    AELSLLEKSL GLSKGNKYSA QGERQIPVLQ TNNGPSLTGL TTIAAHLVKQ

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- EEF1E1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

    Hintergrund

    This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

    Alias Symbols: P18, AIMP3

    Protein Size: 174

    Gen-ID

    9521

    NCBI Accession

    NM_001135650, NP_001129122

    UniProt

    O43324
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