Mitochondrial Calcium Uptake 1 (MICU1) (N-Term) Peptid
MICU1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5672989
Kurzübersicht für Mitochondrial Calcium Uptake 1 (MICU1) (N-Term) Peptid (ABIN5672989)
Target
MICU1
(Mitochondrial Calcium Uptake 1 (MICU1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- CVDNLKSDIG DKGKNKDEGD VCNHEKKTAD LAPHPEEKKK KRSGFRDRKV
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CBARA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
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Hintergrund
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This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: CALC, EFHA3, MPXPS, CBARA1
Protein Size: 403 -
Gen-ID
- 10367
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NCBI Accession
- NM_001195518, NP_001182447
Target
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