Regulator of G-Protein Signaling 14 (RGS14) (C-Term) Peptid
Kurzübersicht für Regulator of G-Protein Signaling 14 (RGS14) (C-Term) Peptid (ABIN5672630)
Target
Spezies
Quelle
Applikation
-
-
Protein Region
- C-Term
-
Sequenz
- ELLNRVQSSG AHDQRGLLRK EDLVLPEFLQ LPAQGPSSEE TPPQTKSAAQ
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- RGS14 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
-
Hintergrund
-
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Protein Size: 347 -
Gen-ID
- 10636
-
NCBI Accession
- NM_006480, NP_006471
Target
-