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Regulator of G-Protein Signaling 14 (RGS14) (C-Term) Peptid

RGS14 Reaktivität: Human Wirt: Synthetic BP, WB

Produktnummer ABIN5672630

Kurzübersicht für Regulator of G-Protein Signaling 14 (RGS14) (C-Term) Peptid (ABIN5672630)

Target

RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Spezies

Human

Quelle

Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

C-Term

Sequenz

ELLNRVQSSG AHDQRGLLRK EDLVLPEFLQ LPAQGPSSEE TPPQTKSAAQ

Produktmerkmale

This is a synthetic peptide designed for use in combination with anti- RGS14 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Regulator of G-Protein Signaling 14 (RGS14) peptide
RGS14 Wirt: Synthetic BP, Imm

Regulator of G-Protein Signaling 14 (RGS14) (Middle Region) peptide
RGS14 Reaktivität: Human, Maus Wirt: Synthetic BP, WB

Regulator of G-Protein Signaling 14 (RGS14) (C-Term) peptide
RGS14 Reaktivität: Ratte Wirt: Synthetic BP, WB

Regulator of G-Protein Signaling 14 (RGS14) peptide
RGS14 Reaktivität: Human Wirt: Synthetic BP, BI

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Lagerung

-20 °C

Informationen zur Lagerung

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Hintergrund

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Protein Size: 347

Gen-ID

10636

NCBI Accession

NM_006480, NP_006471

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