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Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (Middle Region) Peptid

CAMK2A Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5672422
  • Target Alle CAMK2A Produkte
    CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    NARRKLKGAI LTTMLATRNF SGGKSGGNKK SDGVKESSES TNTTIEDEDT
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- CAMK2A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
    Synonyme
    camk2 Peptide, camk2b Peptide, zgc:112538 Peptide, zgc:123320 Peptide, CAMKA Peptide, CaMKII Peptide, R74975 Peptide, mKIAA0968 Peptide, PK2CDD Peptide, PKCCD Peptide, calcium/calmodulin dependent protein kinase II alpha Peptide, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog Peptide, calcium/calmodulin-dependent protein kinase II alpha Peptide, CAMK2A Peptide, camk2a.S Peptide, camk2a Peptide, Camk2a Peptide
    Hintergrund
    The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

    Alias Symbols: CAMKA

    Protein Size: 478
    Gen-ID
    815
    NCBI Accession
    NM_171825, NP_741960
    UniProt
    Q9UQM7
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