This is a synthetic peptide designed for use in combination with anti- CAMK2A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
CAMK2A
Reaktivität: Human, Maus
Wirt: Synthetic
BP, BI
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
CAMK2A
(Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
Synonyme
camk2 Peptide, camk2b Peptide, zgc:112538 Peptide, zgc:123320 Peptide, CAMKA Peptide, CaMKII Peptide, R74975 Peptide, mKIAA0968 Peptide, PK2CDD Peptide, PKCCD Peptide, calcium/calmodulin dependent protein kinase II alpha Peptide, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog Peptide, calcium/calmodulin-dependent protein kinase II alpha Peptide, CAMK2A Peptide, camk2a.S Peptide, camk2a Peptide, Camk2a Peptide
Hintergrund
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.