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Actin-Like 6B (ACTL6B) (Middle Region) Peptid

ACTL6B Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5672388
  • Target Alle Actin-Like 6B (ACTL6B) Produkte
    Actin-Like 6B (ACTL6B)
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    YMIAAKEPVR EGAPPNWKKK EKLPQVSKSW HNYMCNEVIQ DFQASVLQVS
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- ACTL6B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Actin-Like 6B (ACTL6B)
    Hintergrund
    The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.

    Alias Symbols: ACTL6, BAF53B, arpNalpha

    Protein Size: 426
    Gen-ID
    51412
    NCBI Accession
    NM_016188, NP_057272
    UniProt
    O94805
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