Transmembrane Channel-Like 6 (TMC6) (N-Term) Peptid
TMC6
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für Transmembrane Channel-Like 6 (TMC6) (N-Term) Peptid (ABIN5672191)
Target
TMC6
(Transmembrane Channel-Like 6 (TMC6))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- TLWRPEGTQS TATLRILASM PSRTIGRSRG AIISQYYNRT VQLRCRSSRP
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- TMC6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TMC6 (Transmembrane Channel-Like 6 (TMC6))
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Hintergrund
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Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.
Alias Symbols: EV1, EVER1, EVIN1, LAK-4P
Protein Size: 805 -
Gen-ID
- 11322
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NCBI Accession
- NM_001127198, NP_001120670
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UniProt
- Q7Z403
Target
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