Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (C-Term) Peptid
EIF2C1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5672141
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (C-Term) Peptid (ABIN5672141)
Target
AGO1 (EIF2C1)
(Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- RSVSIPAPAY YARLVAFRAR YHLVDKEHDS GEGSHISGQS NGRDPQALAK
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- EIF2C1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) peptide
EIF2C1 Reaktivität: Human, Hund, Maus, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
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Hintergrund
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This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
Alias Symbols: Q99, EIF2C, hAgo1, EIF2C1, GERP95
Protein Size: 857 -
Gen-ID
- 26523
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NCBI Accession
- NM_012199, NP_036331
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UniProt
- Q9UL18
Target
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