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Cadherin 8 (CDH8) (C-Term) Peptid

CDH8 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5672086
  • Target Alle Cadherin 8 (CDH8) Produkte
    Cadherin 8 (CDH8)
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    QIYGYEGRGS VAGSLSSLES TTSDSDQNFD YLSDWGPRFK RLGELYSVGE
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- CDH8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Cadherin 8 (CDH8)
    Hintergrund
    This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.

    Alias Symbols: Nbla04261

    Protein Size: 799
    Gen-ID
    1006
    NCBI Accession
    NM_001796, NP_001787
    UniProt
    P55286
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