Bardet-Biedl Syndrome 4 (BBS4) (N-Term) Peptid
BBS4
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5672066
Kurzübersicht für Bardet-Biedl Syndrome 4 (BBS4) (N-Term) Peptid (ABIN5672066)
Target
BBS4
(Bardet-Biedl Syndrome 4 (BBS4))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- TESQKPRQKK APEFPILEKQ NWLIHLHYIR KDYEACKAVI KEQLQETQGL
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- BBS4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
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Hintergrund
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This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with seven other BBS proteins. Alternate splicing results in multiple transcript variants.
Protein Size: 519 -
Gen-ID
- 585
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NCBI Accession
- NM_001252678, NP_001239607
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UniProt
- Q96RK4
Target
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