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SET Domain and Mariner Transposase Fusion Gene (SETMAR) (Middle Region) Peptid

SETMAR Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5671864
  • Target Alle SETMAR Produkte
    SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    VDPTYIGNIG RFLNHSCEPN LLMIPVRIDS MVPKLALFAA KDIVPEEELS
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- SETMAR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
    Synonyme
    HsMar1 Peptide, METNASE Peptide, Mar1 Peptide, 5830404F24Rik Peptide, Etet2 Peptide, SETMAR Peptide, zgc:172212 Peptide, SET domain and mariner transposase fusion gene Peptide, SET domain without mariner transposase fusion Peptide, histone-lysine N-methyltransferase SETMAR Peptide, SETMAR Peptide, Setmar Peptide, LOC470738 Peptide, setmar Peptide, LOC703880 Peptide, LOC100447656 Peptide, LOC100586616 Peptide
    Hintergrund
    This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

    Alias Symbols: Mar1, HsMar1, METNASE

    Protein Size: 365
    Gen-ID
    6419
    NCBI Accession
    NM_001243723, NP_001230652
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