Nibrin (NBN) (C-Term) Peptid
NBN
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle Nibrin (NBN) Produkte
- Nibrin (NBN)
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- DKLQDDSEML PKKLLLTEFR SLVIKNSTSR NPSGINDDYG QLKNFKKFKK
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- NBN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Nibrin (NBN)
- Synonyme
- NBN Peptide, AT-V1 Peptide, AT-V2 Peptide, ATV Peptide, NBS Peptide, NBS1 Peptide, P95 Peptide, Nbs1 Peptide, im:6911679 Peptide, zgc:194152 Peptide, nibrin Peptide, NBN Peptide, nbn Peptide, Nbn Peptide
- Hintergrund
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Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Alias Symbols: ATV, NBS, P95, NBS1, AT-V1, AT-V2
Protein Size: 754 - Gen-ID
- 4683
- NCBI Accession
- NM_001024688, NP_001019859
- UniProt
- O60934
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