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Nuclear Receptor Binding Factor 2 (NRBF2) (Middle Region) Peptid

NRBF2 Reaktivität: Human Wirt: Synthetic BP, WB

Produktnummer ABIN5671732

Datenblatt (PDF)

Kurzübersicht für Nuclear Receptor Binding Factor 2 (NRBF2) (Middle Region) Peptid (ABIN5671732)

Target

NRBF2 (Nuclear Receptor Binding Factor 2 (NRBF2))

Spezies

Human

Quelle

Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

Middle Region

Sequenz

EFLVAENERL RKENKQLKAE KARLLKGPIE KELDVDADFV ETSELWSLPP

Produktmerkmale

This is a synthetic peptide designed for use in combination with anti- NRBF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Nuclear Receptor Binding Factor 2 (NRBF2) peptide
NRBF2 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC

Nuclear Receptor Binding Factor 2 (NRBF2) (Middle Region) peptide
NRBF2 Reaktivität: Human Wirt: Synthetic BP, WB

Nuclear Receptor Binding Factor 2 (NRBF2) (N-Term) peptide
NRBF2 Reaktivität: Human Wirt: Synthetic BP, WB

Nuclear Receptor Binding Factor 2 (NRBF2) (N-Term) peptide
NRBF2 Reaktivität: Human, Maus Wirt: Synthetic BP, WB

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Lagerung

-20 °C

Informationen zur Lagerung

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

NRBF2 (Nuclear Receptor Binding Factor 2 (NRBF2))

Hintergrund

May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy. Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3. Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1. May be involved in autophagosome biogenesis. May play a role in neural progenitor cell survival during differentiation.

Alias Symbols: COPR, COPR1, COPR2, NRBF-2

Protein Size: 287

Gen-ID

29982

NCBI Accession

NM_001282405, NP_001269334

UniProt

Q96F24

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