HNF1 Homeobox B (HNF1B) (N-Term) Peptid
HNF1B
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5671627
Kurzübersicht für HNF1 Homeobox B (HNF1B) (N-Term) Peptid (ABIN5671627)
Target
HNF1B
(HNF1 Homeobox B (HNF1B))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- AKGRLSGDEG SEDGDDYDTP PILKELQALN TEEAAEQRAE VDRMLSEDPW
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- HNF1B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNF1B (HNF1 Homeobox B (HNF1B))
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Hintergrund
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This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FJHN, HNF2, LFB3, TCF2, HPC11, LF-B3, MODY5, TCF-2, VHNF1, HNF-1B, HNF1beta, HNF-1-beta
Protein Size: 427 -
Gen-ID
- 6928
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NCBI Accession
- NM_000458, NP_000449
Target
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