HNF1 Homeobox A (HNF1A) (Middle Region) Peptid
HNF1A
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle HNF1A Produkte
- HNF1A (HNF1 Homeobox A (HNF1A))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- REVAQQFTHA GQGGLIEEPT GDELPTKKGR RNRFKWGPAS QQILFQAYER
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- HNF1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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HNF1 Homeobox A (HNF1A) peptide
HNF1A Reaktivität: Human, Hund, Maus, Ratte Wirt: Synthetic BP, Imm
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HNF1A (HNF1 Homeobox A (HNF1A))
- Hintergrund
-
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: HNF1, LFB1, TCF1, MODY3, TCF-1, HNF-1A, IDDM20
Protein Size: 524 - Gen-ID
- 6927
- NCBI Accession
- NM_000545, NP_000536
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