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HNF1 Homeobox A (HNF1A) (Middle Region) Peptid

HNF1A Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5671625

Kurzübersicht für HNF1 Homeobox A (HNF1A) (Middle Region) Peptid (ABIN5671625)

Target

HNF1A (HNF1 Homeobox A (HNF1A))

Spezies

Human

Quelle

  • 7
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    REVAQQFTHA GQGGLIEEPT GDELPTKKGR RNRFKWGPAS QQILFQAYER

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- HNF1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HNF1A (HNF1 Homeobox A (HNF1A))

    Hintergrund

    The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: HNF1, LFB1, TCF1, MODY3, TCF-1, HNF-1A, IDDM20

    Protein Size: 524

    Gen-ID

    6927

    NCBI Accession

    NM_000545, NP_000536
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