This is a synthetic peptide designed for use in combination with anti- POLB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
POLB
(Polymerase (DNA Directed), beta (POLB))
Synonyme
wu:fa97a05 Peptide, zgc:109924 Peptide, POLB Peptide, DDBDRAFT_0186152 Peptide, DDBDRAFT_0215784 Peptide, DDBDRAFT_0232376 Peptide, DDB_0186152 Peptide, DDB_0215784 Peptide, DDB_0232376 Peptide, A430088C08Rik Peptide, polymerase (DNA directed), beta Peptide, DNA polymerase beta Peptide, DNA polymerase X family protein Peptide, polymerase (DNA directed), beta S homeolog Peptide, polb Peptide, POLB Peptide, polB Peptide, polb.S Peptide, Polb Peptide
Hintergrund
The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.