Cortactin (CTTN) (Middle Region) Peptid
CTTN
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5671529
Kurzübersicht für Cortactin (CTTN) (Middle Region) Peptid (ABIN5671529)
Target
Cortactin (CTTN)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- KDKVDKSAVG FEYQGKTEKH ESQKDYVKGF GGKFGVQTDR QDKCALGWDH
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CTTN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Cortactin (CTTN)
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Hintergrund
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This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Alias Symbols: EMS1
Protein Size: 634 -
Gen-ID
- 2017
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NCBI Accession
- NM_001184740, NP_001171669
Target
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