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TP53RK Binding Protein (TPRKB) (N-Term) Peptid

TPRKB Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5671497
  • Target Alle TPRKB Produkte
    TPRKB (TP53RK Binding Protein (TPRKB))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    LTHQLDLFPE CRVTLLLFKD VKNAGDLRRK AMEGTIDGSL INPTVIVDPF
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- TPRKB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TPRKB (TP53RK Binding Protein (TPRKB))
    Hintergrund
    Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.

    Alias Symbols: CGI-121

    Protein Size: 214
    Gen-ID
    51002
    NCBI Accession
    NM_016058, NP_057142
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