rho GTPase Activating Protein 26 (ARHGAP26) (Middle Region) Peptid
ARHGAP26
Reaktivität: Human
Wirt: Synthetic
WB
Produktnummer ABIN5671434
Kurzübersicht für rho GTPase Activating Protein 26 (ARHGAP26) (Middle Region) Peptid (ABIN5671434)
Target
GRAF (ARHGAP26)
(rho GTPase Activating Protein 26 (ARHGAP26))
Spezies
Human
Quelle
Synthetic
Applikation
Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- LWMEAMDGRE PVYNSNKDSQ SEGTAQLDSI GFSIIRKCIH AVETRGINEQ
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RHG26 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
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Hintergrund
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Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ARHGAP26,GRAF,KIAA0621,OPHN1L,
Protein Size: 814 -
Gen-ID
- 23092
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NCBI Accession
- NP_055886
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UniProt
- Q9UNA1
Target
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