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Homeobox Protein Nkx-2.4 (LOC105228315) Peptid

LOC105228315 Reaktivität: Human Wirt: Synthetic WB
Produktnummer ABIN5671334

Kurzübersicht für Homeobox Protein Nkx-2.4 (LOC105228315) Peptid (ABIN5671334)

Target

NKX21 (LOC105228315) (Homeobox Protein Nkx-2.4 (LOC105228315))

Spezies

Human

Quelle

Synthetic

Applikation

Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-NKX21 antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    NKX21 (LOC105228315) (Homeobox Protein Nkx-2.4 (LOC105228315))

    Hintergrund

    This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

    Alias Symbols: NKX2A, TITF1, TTF1

    Protein Size: 371

    Molekulargewicht

    40 kDa

    Gen-ID

    7080

    NCBI Accession

    NP_003308

    UniProt

    P43699
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