Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) (Middle Region) Peptid
MAPKAPK5
Reaktivität: Human
Wirt: Synthetic
WB
Produktnummer ABIN5518501
Kurzübersicht für Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) (Middle Region) Peptid (ABIN5518501)
Target
MAPKAP Kinase 5 (MAPKAPK5)
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
Spezies
Human
Quelle
Synthetic
Applikation
Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- TPYTYNKSCD LWSLGVIIYV MLCGYPPFYS KHHSRTIPKD MRRKIMTGSF
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
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Hintergrund
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The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alias Symbols: MK5, MK-5, PRAK, MAPKAP-K5
Protein Size: 473 -
Gen-ID
- 8550
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NCBI Accession
- NM_003668, NP_003659
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UniProt
- Q8IW41
Target
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