Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (N-Term) Peptid
GAD2
Reaktivität: Human
Wirt: Synthetic
WB
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- Target Alle GAD65 (GAD2) Produkte
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Western Blotting (WB)
- Sequenz
- FWSFGSEDGS GDSENPGTAR AWCQVAQKFT GGIGNKLCAL LYGDAEKPAE
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
- Synonyme
- GAD65 Peptide, gad65 Peptide, F12P19.12 Peptide, F12P19_12 Peptide, GLUTAMATE DECARBOXYLASE 2 Peptide, glutamate decarboxylase 2 Peptide, zgc:112198 Peptide, 6330404F12Rik Peptide, GAD(65) Peptide, Gad-2 Peptide, glutamate decarboxylase 2 Peptide, glutamate decarboxylase 1 Peptide, glutamic acid decarboxylase 2 Peptide, GAD2 Peptide, PTRG_06148 Peptide, LOC9324534 Peptide, Gad2 Peptide, GAD1 Peptide, gad2 Peptide
- Hintergrund
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This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Alias Symbols: GAD65,
Protein Size: 585 - Gen-ID
- 2572
- NCBI Accession
- NM_000818, NP_000809
- UniProt
- Q05329
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