Hepcidin Antimicrobial Peptide (HAMP) (Middle Region) Peptid
Kurzübersicht für Hepcidin Antimicrobial Peptide (HAMP) (Middle Region) Peptid (ABIN5518385)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Sequenz
- WAACLLLLLL LASLTSGSVF PQQTGQLAEL QPQDRAGARA SWMPMFQRRR
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Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)
HAMP Reaktivität: Human Wirt: Synthetic WB, Imm, SDS
Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)HAMP Reaktivität: Rind (Kuh) Wirt: Synthetic WB, Imm, SDS
Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)HAMP Reaktivität: Human Wirt: Synthetic WB, Imm, SDS
Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)HAMP Reaktivität: Rind (Kuh) Wirt: Synthetic WB, Imm, SDS
Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)HAMP Reaktivität: Human Wirt: Synthetic WB, Imm, SDS
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
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Hintergrund
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The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.
Alias Symbols: HEPC, PLTR, HFE2B, LEAP1
Protein Size: 113 -
Gen-ID
- 57817
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NCBI Accession
- NM_021175, NP_066998
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UniProt
- P81172
Target
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