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Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Middle Region) Peptid

SIGLEC8 Reaktivität: Human Wirt: Synthetic WB
Produktnummer ABIN5518360
  • Target Alle SIGLEC8 Produkte
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Western Blotting (WB)
    Sequenz
    VRSCRKKSAR PAAGVGDTGM EDAKAIRGSA SQGPLTESWK DGNPLKKPPP
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Synonyme
    SAF2 Peptide, SIGLEC-8 Peptide, SIGLEC8L Peptide, SIGLEC8 Peptide, sialic acid binding Ig like lectin 8 Peptide, sialic acid-binding Ig-like lectin 8 Peptide, SIGLEC8 Peptide, LOC506364 Peptide
    Hintergrund
    Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]

    Alias Symbols: SAF2, SIGLEC-8, SIGLEC8L

    Protein Size: 201
    Gen-ID
    27181
    NCBI Accession
    NM_014442, NP_055257
    UniProt
    Q9NYZ4
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