Pescadillo Ribosomal Biogenesis Factor 1 (PES1) (Middle Region) Peptid
PES1
Reaktivität: Human
Wirt: Synthetic
WB
Produktnummer ABIN5518322
Kurzübersicht für Pescadillo Ribosomal Biogenesis Factor 1 (PES1) (Middle Region) Peptid (ABIN5518322)
Target
PES1
(Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
Spezies
Human
Quelle
Synthetic
Applikation
Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- LLALQRGEDP GNLNESEEEE EEDDNNEGDG DEEGENEEEE EDAEAGSEKE
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
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Hintergrund
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This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.
Alias Symbols: PES
Protein Size: 167 -
Gen-ID
- 23481
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NCBI Accession
- NM_001243225, NP_001230154
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UniProt
- O00541
Target
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