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TNF Receptor-Associated Factor 3 (TRAF3) (C-Term) Peptid

TRAF3 Reaktivität: Human Wirt: Synthetic WB
Produktnummer ABIN5518223
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für TNF Receptor-Associated Factor 3 (TRAF3) (C-Term) Peptid (ABIN5518223)

Target

TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    MLMDQGSSRR HLGDAFKPDP NSSSFKKPTG EMNIASGCPV FVAQTVLENG
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

    Hintergrund

    The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.

    Alias Symbols: CAP1, LAP1, CAP-1, CRAF1, IIAE5, CD40bp

    Protein Size: 167

    Gen-ID

    7187

    NCBI Accession

    NM_001199427, NP_001186356

    UniProt

    Q13114
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